Robert S. Chapkin, PhD
Deputy Director, Center of Excellence in Cancer Research
Allen Endowed Chair in Nutrition & Chronic Disease Prevention
University Distinguished Professor
Regents Professor & University Faculty Fellow
Contact
Office: CMAT/111
r-chapkin@tamu.edu
Phone: 979.845.0419
Chapkin Lab
Google Scholar
Biography
Robert S. Chapkin is an NIH/NCI R35-Outstanding Investigator Awardee and an American Association for the Advancement of Science (AAAS) Fellow. He has made highly significant precision medicine related contributions including seminal cancer prevention strategies to delineate host responses to environmental (diet-derived) and endogenous (gut microbial) bioactive agents.
For the past 35 years, the Chapkin lab has evaluated (using preclinical models and human subjects) how diet and the gut microbiome modulate intestinal epithelial and immune cell biology in the context of colon cancer. As part of this endeavor, the hierarchical cellular organization of the intestinal stem cell niche was modeled. Work in the lab falls into four specific areas:
- Role of dietary and microbial Ligands as modifiers of colon cancer RISk.
- HOW DIETARY INTERACTIONS MODULATE INTESTINAL HOMEOSTASIS.
- Effects of diet related nioactives on plasma membrane homeostasis.
- Development of novel noninvasive methodology to monitor HOST/MICROBE interaction in the gut.